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Plasma obtained following murine hindlimb ischemic conditioning protects against oxidative stress in zebrafish models through activation of nrf2a and downregulation of duox.
Guan, Rui; Wen, Xiao-Yan; Leung, Chung Ho; Ciano-Oliveira, Caterina Di; Lam, Stephen; Dai, Si Yuan; Karbassi, Farhad; Mauro, Antonio; Wang, Youdong; Rotstein, Ori.
Afiliação
  • Guan R; Zebrafish Centre for Advanced Drug Discovery, The Keenan Research Centre for Biomedical Science Toronto, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Ontario, Canada.
  • Wen XY; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
  • Leung CH; Zebrafish Centre for Advanced Drug Discovery, The Keenan Research Centre for Biomedical Science Toronto, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Ontario, Canada.
  • Ciano-Oliveira CD; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
  • Lam S; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
  • Dai SY; Departments of Surgery, St. Michael's Hospital and University of Toronto, Toronto, Ontario, Canada.
  • Karbassi F; Zebrafish Centre for Advanced Drug Discovery, The Keenan Research Centre for Biomedical Science Toronto, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Ontario, Canada.
  • Mauro A; Departments of Surgery, St. Michael's Hospital and University of Toronto, Toronto, Ontario, Canada.
  • Wang Y; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
  • Rotstein O; Department of Medicine & Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.
PLoS One ; 16(11): e0260442, 2021.
Article em En | MEDLINE | ID: mdl-34818339
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Peixe-Zebra / Estresse Oxidativo / NADPH Oxidases / Precondicionamento Isquêmico / Proteínas de Peixe-Zebra / Fator 2 Relacionado a NF-E2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasma / Peixe-Zebra / Estresse Oxidativo / NADPH Oxidases / Precondicionamento Isquêmico / Proteínas de Peixe-Zebra / Fator 2 Relacionado a NF-E2 Idioma: En Ano de publicação: 2021 Tipo de documento: Article