Ultra-small natural product based coordination polymer nanodots for acute kidney injury relief.
Mater Horiz
; 8(4): 1314-1322, 2021 04 01.
Article
em En
| MEDLINE
| ID: mdl-34821924
ABSTRACT
Acute kidney injury (AKI) is frequently associated with reactive oxygen species (ROS) and causes high mortality in clinics annually, and nanotechnology-mediated antioxidative therapy is emerging as a novel strategy for AKI treatment. Herein, four kinds of natural antioxidants are able to coordinate with iron (Fe) ions to form ultra-small coordination polymer nanodots (CPNs) with good water dispersibility and strong ROS scavenging ability. In particular, Fe-curcumin CPNs (Fe-Cur CPNs) are applied for cellular ROS scavenging and rhabdomyolysis-induced AKI relief.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Injúria Renal Aguda
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article