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Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.
Ansari-Pour, Naser; Zheng, Yonglan; Yoshimatsu, Toshio F; Sanni, Ayodele; Ajani, Mustapha; Reynier, Jean-Baptiste; Tapinos, Avraam; Pitt, Jason J; Dentro, Stefan; Woodard, Anna; Rajagopal, Padma Sheila; Fitzgerald, Dominic; Gruber, Andreas J; Odetunde, Abayomi; Popoola, Abiodun; Falusi, Adeyinka G; Babalola, Chinedum Peace; Ogundiran, Temidayo; Ibrahim, Nasiru; Barretina, Jordi; Van Loo, Peter; Chen, Mengjie; White, Kevin P; Ojengbede, Oladosu; Obafunwa, John; Huo, Dezheng; Wedge, David C; Olopade, Olufunmilayo I.
Afiliação
  • Ansari-Pour N; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LF, UK.
  • Zheng Y; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Yoshimatsu TF; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Sanni A; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Ajani M; Department of Pathology and Forensic Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
  • Reynier JB; Department of Pathology, University of Ibadan, Ibadan, Oyo, Nigeria.
  • Tapinos A; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Pitt JJ; Manchester Cancer Research Centre, University of Manchester, Manchester, M20 4GJ, UK.
  • Dentro S; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
  • Woodard A; European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge, CB10 1SD, UK.
  • Rajagopal PS; Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.
  • Fitzgerald D; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Gruber AJ; Department of Computer Science, The University of Chicago, Chicago, IL, 60637, USA.
  • Odetunde A; Center for Clinical Cancer Genetics and Global Health, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Popoola A; Institute for Genomics and Systems Biology, University of Chicago, Chicago, IL, 60637, USA.
  • Falusi AG; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LF, UK.
  • Babalola CP; Manchester Cancer Research Centre, University of Manchester, Manchester, M20 4GJ, UK.
  • Ogundiran T; Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.
  • Ibrahim N; Oncology Unit, Department of Radiology, Lagos State University, Ikeja, Lagos, Nigeria.
  • Barretina J; Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.
  • Van Loo P; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan, Ibadan, Oyo, Nigeria.
  • Chen M; Department of Surgery, University College Hospital, Ibadan, Oyo, Nigeria.
  • White KP; Department of Surgery, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
  • Ojengbede O; Girona Biomedical Research Institute (IDIBGI), Hospital Universitari de Girona Dr Josep Trueta, Girona, Spain.
  • Obafunwa J; The Francis Crick Institute, London, NW1 1AT, UK.
  • Huo D; Department of Human Genetics, The University of Chicago, Chicago, IL, 60637, USA.
  • Wedge DC; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL, 60637, USA.
  • Olopade OI; Tempus Labs Inc., Chicago, IL, 60654, USA.
Nat Commun ; 12(1): 6946, 2021 11 26.
Article em En | MEDLINE | ID: mdl-34836952
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biomarcadores Tumorais / Disparidades nos Níveis de Saúde / Evolução Clonal Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Biomarcadores Tumorais / Disparidades nos Níveis de Saúde / Evolução Clonal Idioma: En Ano de publicação: 2021 Tipo de documento: Article