Phospholipase A2 group IIA correlates with circulating high-density lipoprotein cholesterol and modulates cholesterol efflux possibly through regulation of PPAR-Î³/LXR-&#945;/ABCA1 in macrophages.

Liang, Ling; Xie, Qiang; Sun, Changqing; Wu, Yuanhui; Zhang, Wei; Li, Weihua

Phospholipase A2 group IIA correlates with circulating high-density lipoprotein cholesterol and modulates cholesterol efflux possibly through regulation of PPAR-Î³/LXR-α/ABCA1 in macrophages.

Liang, Ling; Xie, Qiang; Sun, Changqing; Wu, Yuanhui; Zhang, Wei; Li, Weihua.

Afiliação

Liang L; Department of Cardiology, Xiamen Key Laboratory of Cardiac Electrophysiology, Xiamen Institute of Cardiovascular Diseases, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Xie Q; Department of Cardiology, The Third Clinical Medical College, Fujian Medical University, Fuzhou, 350122, China.
Sun C; Department of Cardiology, Xiamen Key Laboratory of Cardiac Electrophysiology, Xiamen Institute of Cardiovascular Diseases, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Wu Y; Department of Cardiology, The Third Clinical Medical College, Fujian Medical University, Fuzhou, 350122, China.
Zhang W; Department of Cardiology, Xiamen Key Laboratory of Cardiac Electrophysiology, Xiamen Institute of Cardiovascular Diseases, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
Li W; Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.

J Transl Med ; 19(1): 484, 2021 11 27.

Article em En | MEDLINE | ID: mdl-34838043

Assuntos

Receptores Nucleares Órfãos; PPAR gama; Transportador 1 de Cassete de Ligação de ATP/genética; Transportadores de Cassetes de Ligação de ATP; Colesterol; HDL-Colesterol; Humanos; Receptores X do Fígado/metabolismo; Macrófagos/metabolismo; Receptores Nucleares Órfãos/metabolismo; Fosfolipases A2

Palavras-chave

ATP-binding cassette A1; Cholesterol efflux; Group IIA secretory phospholipase A2; High-density lipoprotein cholesterol; Peroxisome proliferator-activated receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR gama / Receptores Nucleares Órfãos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR gama / Receptores Nucleares Órfãos Idioma: En Ano de publicação: 2021 Tipo de documento: Article