Fluorescence Imaging of Mitochondrial DNA Base Excision Repair Reveals Dynamics of Oxidative Stress Responses.

Jun, Yong Woong; Albarran, Eddy; Wilson, David L; Ding, Jun; Kool, Eric T

Jun, Yong Woong; Albarran, Eddy; Wilson, David L; Ding, Jun; Kool, Eric T.

Afiliação

Jun YW; Department of Chemistry, ChEM-H Institute, and Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.
Albarran E; Department of Neurosurgery, Department of Neurology and Neurological Sciences, and Wu Tsai Neuroscience institute, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Wilson DL; Department of Chemistry, ChEM-H Institute, and Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.
Ding J; Department of Neurosurgery, Department of Neurology and Neurological Sciences, and Wu Tsai Neuroscience institute, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Kool ET; Department of Chemistry, ChEM-H Institute, and Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.

Angew Chem Int Ed Engl ; 61(6): e202111829, 2022 02 01.

Article em En | MEDLINE | ID: mdl-34851014

Assuntos

DNA Mitocondrial/análise; Corantes Fluorescentes/química; Imagem Óptica; Animais; Células Cultivadas; Reparo do DNA; DNA Mitocondrial/metabolismo; Células HeLa; Humanos; Camundongos; Estresse Oxidativo

Palavras-chave

AP sites; DNA damage; base excision repair; fluorescence probes; mitochondrial DNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Imagem Óptica / Corantes Fluorescentes Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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