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Correlation of dried blood spots and plasma for quantification of Immunoglobulin (IgG) against Receptor binding domain and full length spike protein of SARS-CoV-2.
Kwatra, Gaurav; Nunes, Marta; Dhar, Nisha; Baillie, Vicky; Serafin, Natali; Jones, Stephanie; Madhi, Shabir A.
Afiliação
  • Kwatra G; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Nunes M; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Dhar N; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Baillie V; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Serafin N; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Jones S; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
  • Madhi SA; South African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/ National Research Foundation: Vaccine Preventable Diseases, University of t
J Virol Methods ; 300: 114394, 2022 02.
Article em En | MEDLINE | ID: mdl-34861318
ABSTRACT
We compared plasma and dried blood spots for detection of SARS-CoV-2 IgG antibodies. There was a good correlation between IgG values measured by both sampling methods, r = 0.935 and 0.965 for Receptor Binding Domain and full-length spike protein of SARS-CoV-2. Bland-Altman assessment showed good agreement between two sampling methods. Dried blood spots is a more pragmatic method for collecting samples for sero-epidemiological surveys of SARS-CoV-2 infection.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Teste em Amostras de Sangue Seco / Glicoproteína da Espícula de Coronavírus / COVID-19 / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Teste em Amostras de Sangue Seco / Glicoproteína da Espícula de Coronavírus / COVID-19 / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article