A survey of the clinical pipeline in neuroscience.
Bioorg Med Chem Lett
; 56: 128482, 2022 01 15.
Article
em En
| MEDLINE
| ID: mdl-34864194
ABSTRACT
Many new first-in-class drugs for neuroscience indications have been introduced in the past decade including new treatments for migraine, amyotrophic lateral sclerosis, depression, and multiple sclerosis. However, significant unmet patient needs remain in areas such as chronic pain, neurodegeneration, psychiatric diseases, and epilepsy. This review summarizes some of the advanced clinical compounds for these indications. Additionally, current opportunities and challenges that remain with respect to genetic validation, biomarkers, and translational models are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Fármacos Neuroprotetores
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Doenças Neurodegenerativas
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Epilepsia
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Dor Crônica
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Transtornos Mentais
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article