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Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Gerber, Julia P; Russ, Jenny; Chandrasekar, Vijay; Offermann, Nina; Lee, Hang-Mao; Spear, Sarah; Guzzi, Nicola; Maida, Simona; Pattabiraman, Sundararaghavan; Zhang, Ruoyu; Kayvanjoo, Amir H; Datta, Preeta; Kasturiarachchi, Jagath; Sposito, Teresa; Izotova, Natalia; Händler, Kristian; Adams, Peter D; Marafioti, Teresa; Enver, Tariq; Wenzel, Jörg; Beyer, Marc; Mass, Elvira; Bellodi, Cristian; Schultze, Joachim L; Capasso, Melania; Nimmo, Rachael; Salomoni, Paolo.
Afiliação
  • Gerber JP; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Russ J; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Chandrasekar V; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Offermann N; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Lee HM; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Spear S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Guzzi N; Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Maida S; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund, Sweden.
  • Pattabiraman S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Zhang R; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Kayvanjoo AH; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Datta P; Life and Medical Sciences (LIMES) Institute, Developmental Biology of the Immune System, University of Bonn, Bonn, Germany.
  • Kasturiarachchi J; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Sposito T; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Izotova N; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Händler K; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Adams PD; Platform for Single Cell Genomics and Epigenomics (PRECISE) at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Marafioti T; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, USA.
  • Enver T; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Wenzel J; Department of Pathology, University College London, London, UK.
  • Beyer M; Department of Cancer Biology, UCL Cancer Institute, London, UK.
  • Mass E; Department of Dermatology and Allergy, University Medical Center, Bonn, Germany.
  • Bellodi C; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
  • Schultze JL; Platform for Single Cell Genomics and Epigenomics (PRECISE) at the German Center for Neurodegenerative Diseases and the University of Bonn, Bonn, Germany.
  • Capasso M; Life and Medical Sciences (LIMES) Institute, Developmental Biology of the Immune System, University of Bonn, Bonn, Germany.
  • Nimmo R; Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund, Sweden.
  • Salomoni P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Nat Cell Biol ; 23(12): 1224-1239, 2021 12.
Article em En | MEDLINE | ID: mdl-34876685
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Transativadores / Proteínas Proto-Oncogênicas / Chaperonas Moleculares / Mielopoese / Proteínas Correpressoras / Transtornos Leucocíticos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatina / Transativadores / Proteínas Proto-Oncogênicas / Chaperonas Moleculares / Mielopoese / Proteínas Correpressoras / Transtornos Leucocíticos Idioma: En Ano de publicação: 2021 Tipo de documento: Article