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HDX-MS and MD Simulations Provide Evidence for Stabilization of the IgG1-FcγRIa (CD64a) Immune Complex Through Intermolecular Glycoprotein Bonds.
Anderson, Kyle W; Bergonzo, Christina; Scott, Kerry; Karageorgos, Ioannis L; Gallagher, Elyssia S; Tayi, Venkata S; Butler, Michael; Hudgens, Jeffrey W.
Afiliação
  • Anderson KW; National Institute of Standards and Technology, Bioprocess Measurements Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: kyle.anderson@nist.
  • Bergonzo C; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA; National Institute of Standards and Technology, Biomolecular Structure and Function Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: christi
  • Scott K; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA; National Institute of Standards and Technology, Bioanalytical Science Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: kscott@meso-scale.com
  • Karageorgos IL; National Institute of Standards and Technology, Bioprocess Measurements Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: ioannis.karageorgos
  • Gallagher ES; National Institute of Standards and Technology, Bioprocess Measurements Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: Elyssia_Gallagher@b
  • Tayi VS; University of Manitoba, Department of Microbiology, Winnipeg, MB R3T 2N2, Canada. Electronic address: venkata.tayi@gmail.com.
  • Butler M; University of Manitoba, Department of Microbiology, Winnipeg, MB R3T 2N2, Canada; National Institute for Bioprocessing Research and Training, 26 Foster's Ave, Belfield, Blackrock, Co. Dublin A94 F5D5, Ireland. Electronic address: michael.butler@nibrt.ie.
  • Hudgens JW; National Institute of Standards and Technology, Bioprocess Measurements Group, Biomolecular Measurement Division, 9600 Gudelsky Drive, Rockville, MD 20850, USA; Institute for Bioscience and Biotechnology Research, 9600 Gudelsky Drive, Rockville, MD 20850, USA. Electronic address: jeffrey.hudgens@nis
J Mol Biol ; 434(2): 167391, 2022 01 30.
Article em En | MEDLINE | ID: mdl-34890647

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Glicoproteínas / Receptores de IgG / Simulação de Dinâmica Molecular / Espectrometria de Massa com Troca Hidrogênio-Deutério / Complexo Antígeno-Anticorpo Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Glicoproteínas / Receptores de IgG / Simulação de Dinâmica Molecular / Espectrometria de Massa com Troca Hidrogênio-Deutério / Complexo Antígeno-Anticorpo Idioma: En Ano de publicação: 2022 Tipo de documento: Article