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A simple hydrazone probe for recognition of Al3+ and PPi and its applicability in lysosomal imaging.
Song, Yu-Fei; Cai, Hong-Xin; Wu, Wei-Na; Zong, Hai-Tao; Li, Ming; Wang, Yuan; Fan, Yun-Chang; Xu, Zhi-Hong.
Afiliação
  • Song YF; College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China.
  • Cai HX; School of Physics and Electronic Information Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China.
  • Wu WN; College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China. Electronic address: wuwn08@hpu.edu.cn.
  • Zong HT; School of Physics and Electronic Information Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China.
  • Li M; School of Physics and Electronic Information Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China.
  • Wang Y; College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China. Electronic address: wangyuan08@hpu.edu.cn.
  • Fan YC; College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo 454000, PR China.
  • Xu ZH; Key Laboratory of Chemo/Biosensing and Detection, School of Chemistry and Chemical Engineering, Xuchang University, 461000, PR China; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450052, PR China. Electronic address: xuzhihong1980@xcu.edu.cn.
Spectrochim Acta A Mol Biomol Spectrosc ; 268: 120680, 2022 Mar 05.
Article em En | MEDLINE | ID: mdl-34906844
A simple hydrazone probe (1) was designed and synthesized for the successive detection of Al3+ and pyrophosphate (PPi) in almost 100% buffer environment. The probe provided O2N donor set for chelation with Al3+, leading to a distinct fluorescence boost at 510 nm. The in-situ formed 1-Al3+ complex detected PPi with an "on-off" behavior. The detection limits for Al3+ and PPi were 35.7 nM and 76 nM, respectively. Benefiting from the existence of morpholine as lysosome-targeting group, probe 1 was successfully applied to the detection of Al3+ and PPi in lysosomes.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Hidrazonas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corantes Fluorescentes / Hidrazonas Idioma: En Ano de publicação: 2022 Tipo de documento: Article