Association between post-traumatic stress disorder and hypertension in Congolese exposed to violence: a case-control study.
J Hypertens
; 40(4): 685-691, 2022 04 01.
Article
em En
| MEDLINE
| ID: mdl-34907991
ABSTRACT
BACKGROUND:
Numerous risk factors have been involved in the pathogenesis of hypertension. The contribution of psychological factors, including post-traumatic stress disorder, remains largely underexplored, despite their potential role in hypertension.OBJECTIVES:
We compared the prevalence of trauma, post-traumatic stress and other psychological disorders between hypertensive and normotensive patients from Bukavu (Democratic Republic of Congo), a 25-year war-exposed city. METHODS ANDMEASURES:
In this case-control study, we assessed past traumatic events with the Stressful-Events-Scale, post-traumatic stress disorder through the post-traumatic diagnostic scale, depression and alcohol use disorder through the MINI-International-Neuropsychiatric-Interview, and emotion regulation through the Emotion-Regulation-Questionnaire in 106 hypertensive and 106 normotensive patients, enrolled at the Bukavu General Hospital.RESULTS:
Compared with normotensive controls (73% women, age 43â±â14âyears, BP 121â±â10/75â±â8âmmHg), hypertensive patients (57% women, age 42â±â13 years, BP 141â±â12/82â±â7âmmHg, on a median of two antihypertensive drugs) were exposed to more man-made traumas (61 vs. 13%, Pâ<â0.001), used more expressive suppression (Pâ=â0.05) and less cognitive reappraisal (Pâ=â0.02) as emotional regulation strategies. They developed more frequent post-traumatic stress disorder (36 vs. 7%, Pâ<â0.001) and major depressive disorder (37 vs. 13%, Pâ=â0.001), often in association with alcohol use disorder (23 vs. 4%, Pâ<â0.001). In multivariate logistic regression, post-traumatic stress disorder [ORâ=â3.52 (1.23-6.54)], man-made trauma [ORâ=â2.24 (1.15-4.12)], family history of hypertension [ORâ=â2.24 (1.06-4.44)], fasting blood glucose [ORâ=â1.85 (1.07-3.08)], BMI [ORâ=â1.28 (1.12-2.92)], expressive suppression [ORâ=â1.23 (1.11-2.23)] and cognitive reappraisal [ORâ=â0.76 (0.63-0.98)] were independent predictors of hypertension.CONCLUSION:
In Congolese populations exposed to war, man-made trauma exposure and post-traumatic stress disorder appear to be more tightly related to hypertension than classical hypertension risk factors.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Transtornos de Estresse Pós-Traumáticos
/
Transtorno Depressivo Maior
/
Hipertensão
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article