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Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity.
Zhao, Fabao; Atxabal, Unai; Mariottini, Sofia; Yi, Feng; Lotti, James S; Rouzbeh, Nirvan; Liu, Na; Bunch, Lennart; Hansen, Kasper B; Clausen, Rasmus P.
Afiliação
  • Zhao F; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
  • Atxabal U; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
  • Mariottini S; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
  • Yi F; Center for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, Montana 59812, United States.
  • Lotti JS; Center for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, Montana 59812, United States.
  • Rouzbeh N; Center for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, Montana 59812, United States.
  • Liu N; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
  • Bunch L; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
  • Hansen KB; Center for Structural and Functional Neuroscience, Center for Biomolecular Structure and Dynamics, Division of Biological Sciences, University of Montana, Missoula, Montana 59812, United States.
  • Clausen RP; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2200, Denmark.
J Med Chem ; 65(1): 734-746, 2022 01 13.
Article em En | MEDLINE | ID: mdl-34918931
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Receptores de N-Metil-D-Aspartato / Agonistas de Aminoácidos Excitatórios / Glicina / Proteínas de Membrana / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Receptores de N-Metil-D-Aspartato / Agonistas de Aminoácidos Excitatórios / Glicina / Proteínas de Membrana / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2022 Tipo de documento: Article