Relationship between magnetic resonance imaging findings and prognosis of intracranial tuberculosis.
Acta Radiol
; 64(1): 267-273, 2023 Jan.
Article
em En
| MEDLINE
| ID: mdl-34923832
ABSTRACT
BACKGROUND:
Intracranial tuberculosis (TB) is an intracranial infection caused by Mycobacterium tuberculosis. Magnetic resonance imaging (MRI), in particular enhanced MRI scan, has the ability to detect characteristic lesions of tuberculous meningitis or cerebral parenchymal TB.PURPOSE:
To analyze the relationship between MRI findings and prognosis of patients with intracranial TB. MATERIAL ANDMETHODS:
In this retrospective study, a total of 60 patients were confirmed with intracranial TB in the hospital from May 2019 to December 2020. All enrolled patients underwent TB-related laboratory examinations, cranial MRI, and contrast-enhanced MRI. Laboratory tests were analyzed and the relationship between clinical prognosis and cranial MRI features was evaluated.RESULTS:
Of the 60 patients, 28 (46.67%) had disseminated TB complications, 20 (36.67%) had secondary TB complications, and the remaining 10 (16.66%) had lymphatic TB or spinal TB complications. Of the patients, 25 had good short-term prognosis and 35 had poor short-term prognosis; 44 patients had good long-term prognosis and 16 had poor long-term prognosis. The incidence of cerebral parenchymal tuberculomas on enhanced MRI was significantly higher in the group with good prognosis compared to that in the group with poor prognosis (P < 0.05). Logistic analysis suggested that hydrocephalus (odds ratio [OR] = 0.057, 95% confidence interval [CI] = 0.003-0.444; P = 0.018) and cistern involvement (OR = 0.100, 95% CI = 0.011-0.581; P = 0.017) were independent risk factors for poor short-term prognosis.CONCLUSION:
MRI can display the pathological changes of intracranial TB in detail; hydrocephalus and cistern involvement were independent risk factors for poor short-term prognosis.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Tuberculoma Intracraniano
/
Hidrocefalia
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article