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Discovery of a novel and orally active Farnesoid X receptor agonist for the protection of acetaminophen-induced hepatotoxicity.
Cai, Zongyu; Wang, Bin; Zhou, Zongtao; Zhao, Xin; Hu, Lijun; Ren, Qiang; Deng, Liming; Li, Zheng; Wang, Guangji.
Afiliação
  • Cai Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Wang B; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Zhou Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Zhao X; Key Laboratory of New Drug Discovery and Evaluation, Guangdong Pharmaceutical University, Guangzhou, China.
  • Hu L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Ren Q; School of Pharmaceutical Sciences, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
  • Deng L; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Li Z; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.
  • Wang G; Key Laboratory of New Drug Discovery and Evaluation, Guangdong Pharmaceutical University, Guangzhou, China.
Chem Biol Drug Des ; 99(3): 483-495, 2022 03.
Article em En | MEDLINE | ID: mdl-34936214
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Citoplasmáticos e Nucleares / Substâncias Protetoras / Doença Hepática Induzida por Substâncias e Drogas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Citoplasmáticos e Nucleares / Substâncias Protetoras / Doença Hepática Induzida por Substâncias e Drogas Idioma: En Ano de publicação: 2022 Tipo de documento: Article