Bone degradation; Bone microbiome; COLL, collagenases (peptidases families U32 and M9); Collagenase; DNS, dinitrosalicylic acid; FALGPA, N-[3-(2-furyl)acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanine; Glycosidase; HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HMM, Hidden Markov Models; HPAEC-PAD, High performance anion-exchange chromatography with pulsed amperometric detection; MAG, Metagenome Assembled Genome; Metagenomics; Neu5Ac-GM2, N-acetyl-galactose-ß-1,4-[N-acetylneuraminidate-α-2,3-]-galactose-ß-1,4-glucose-α-ceramide; Neu5Ac-GM3, Neu5Acα2-3Galß1-4Glcß1-ceramide; Ni-NTA, nickel-nitrilotriacetic acid; Osedax mucofloris; PEPT, peptidase (families S1, S8, S53, M61); RHAM, α-rhamnosidases; SIAL, sialidases; pNP-NAßGal, pNP-N-acetyl-ß-galactosaminide; pNP-NAßGlu, pNP-N-acetyl-ß-glucosaminide; pNP-Neu5Ac, 2-O-(p-nitrophenyl)-α-acetylneuraminic acid; pNP-sugars, p-nitrophenyl-sugars; pNP-αAFur, pNP-α-arabinofuranoside; pNP-αAPyr, pNP-α-arabinopyranoside; pNP-αFuc, pNP-α-fucopyranoside; pNP-αGal, pNP-α-galactopyranoside; pNP-αGlu, pNP-α-glucopyranoside; pNP-αMal, pNP-α-maltoside; pNP-αMan, pNP-α-mannopyranoside; pNP-αRham, pNP-α-rhamnopyranoside; pNP-αXyl, pNP-α-xylopyranoside; pNP-ßAPyr, pNP-ß-arabinopyranoside; pNP-ßCel, pNP-ß-cellobioside; pNP-ßFuc, pNP-ß-fucopyranoside; pNP-ßGal, pNP-ß-galactopyranoside; pNP-ßGlu, pNP-ß-glucopyranoside; pNP-ßGlucur, pNP-ß-glucuronide; pNP-ßLac, pNP-ß-lactoside; pNP-ßMan, pNP-ß-mannopyranoside; pNP-ßXyl, pNP-ß-xylopyranoside; αFUC, α-fucosidases; αGAL, α-galactosidases; αMAN, α-mannosidases; αNAG, α-N-acetyl-hexosaminidases; ßGAL, ß-galactosidases; ßGLU, ß-glucosidases; ßNAG, ß-N-acetyl-hexosaminidases