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Nanoparticles Mediated Target-specific Drug Delivery in Prostate Cancer: An In-depth Review.
Upadhyay, Tarun Kumar; Ali, Mohammed Irfan; Khan, Fahad; Goel, Harsh; Mathur, Manas; Goyal, Keshav; Moin, Sarmad; Pandey, Pratibha; Tanwar, Pranay; Sharangi, Amit Baran; Gautam, Saloni Dinesh Chandra; Kapdi, Jhanvi Kiran; Patel, Kruti Indravadan; Patel, Meghna Vipulbhai; Parmar, Amisha M; Kamal, Mohammad Amjad.
Afiliação
  • Upadhyay TK; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Ali MI; Faculty of Life Sciences, Mandsaur University, Mandsaur, 458001, Madhya Pradesh, India.
  • Khan F; Department of Biotechnology, Noida Institute of Engineering & Technology, Greater Noida, 201306, India.
  • Goel H; Department of Laboratory Oncology, All India Institute of Medical Sciences, New Delhi, India.
  • Mathur M; School of Agriculture, Suresh Gyan Vihar University, Jaipur, 302017, India.
  • Goyal K; Department of Microbiology, Ram Lal Anand College, University of Delhi, India.
  • Moin S; School of Applied Sciences, Suresh Gyan Vihar University, Jaipur, 302017, Rajasthan, India.
  • Pandey P; Department of Biotechnology, Noida Institute of Engineering & Technology, Greater Noida, 201306, India.
  • Tanwar P; Department of Laboratory Oncology, All India Institute of Medical Sciences, New Delhi, India.
  • Sharangi AB; Department of Plantation, Spices, Medicinal & Aromatic Crops, BCKV-Agricultural University, Mohanpur, Nadia, West Bengal, India.
  • Gautam SDC; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Kapdi JK; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Patel KI; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Patel MV; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Parmar AM; Department of Biotechnology, Animal Cell Culture and Immunobiochemistry Lab, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara, Gujarat, 391760, India.
  • Kamal MA; West China School of Nursing / Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
Curr Med Chem ; 29(24): 4170-4184, 2022.
Article em En | MEDLINE | ID: mdl-34939536
Nanotechnology has been extensively exploited for its enormous therapeutic and diagnostic potential in the management of multiple disorders. It employs nanomaterials as drug carriers with enhanced efficacy and limited side effects on normal tissues. A lot of nanomaterials have been studied and produced, imminently reforming the treatment and diagnostics of numerous malignancies, including cancer. The purpose of the present study is to explore the role of nanotechnology-based devices/therapies that have a vital function in the therapeutics and diagnostics of cancer with potential impact at three levels: early detection, tumor imaging, and drug delivery methods. Concentrating on cancer, promising nanotechnology-based approaches have been planned to satisfy the need for targeted specificity of traditional agents of chemotherapeutics, in addition to early recognition of malignant and precancerous lesions. Prostate cancer is the fifth most wellknown cancer worldwide and the second most usually detected cancer in men. Therefore, there is a crucial need to improve therapeutic prospects for the diagnosis and treatment of prostate cancer via the exploitation of the potential of nanomaterials for cell-targeted specificity and improved primary diagnosis of precancerous tumors. The present review, therefore, focuses on summarizing all prospective applications of nanotechnology in the prognosis and diagnosis of prostate cancer, which would further help researchers to elucidate a more potent therapeutic approach for the better management of prostate cancer in the days ahead.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article