Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis.

Reske, Jake J; Wilson, Mike R; Holladay, Jeanne; Siwicki, Rebecca A; Skalski, Hilary; Harkins, Shannon; Adams, Marie; Risinger, John I; Hostetter, Galen; Lin, Ken; Chandler, Ronald L

Reske, Jake J; Wilson, Mike R; Holladay, Jeanne; Siwicki, Rebecca A; Skalski, Hilary; Harkins, Shannon; Adams, Marie; Risinger, John I; Hostetter, Galen; Lin, Ken; Chandler, Ronald L.

Afiliação

Reske JJ; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Wilson MR; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Holladay J; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Siwicki RA; Genomics Core Facility, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.
Skalski H; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Harkins S; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Adams M; Genomics Core Facility, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.
Risinger JI; Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.
Hostetter G; Department of Women's Health, Spectrum Health System, Grand Rapids, Michigan, United States of America.
Lin K; Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, Michigan, United States of America.
Chandler RL; Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, New York, New York, United States of America.

PLoS Genet ; 17(12): e1009986, 2021 12.

Article em En | MEDLINE | ID: mdl-34941867

Assuntos

Proteínas de Ligação a DNA/genética; Neoplasias do Endométrio/genética; Fatores de Transcrição/genética; Proteína Supressora de Tumor p53/genética; Proteínas Supressoras de Tumor/genética; Adenocarcinoma/genética; Adenocarcinoma/patologia; Animais; Carcinogênese/genética; Carcinoma in Situ/genética; Carcinoma in Situ/patologia; Classe I de Fosfatidilinositol 3-Quinases/genética; Hiperplasia Endometrial/genética; Hiperplasia Endometrial/patologia; Neoplasias do Endométrio/patologia; Endométrio/patologia; Transição Epitelial-Mesenquimal/genética; Feminino; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Camundongos; Mutação/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteína Supressora de Tumor p53 / Neoplasias do Endométrio / Proteínas Supressoras de Tumor / Proteínas de Ligação a DNA Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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