Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases.

Santucci, Matteo; Luciani, Rosaria; Gianquinto, Eleonora; Pozzi, Cecilia; Pisa, Flavio di; Dello Iacono, Lucia; Landi, Giacomo; Tagliazucchi, Lorenzo; Mangani, Stefano; Spyrakis, Francesca; Costi, Maria Paola.

Afiliação

Santucci M; Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
Luciani R; Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
Gianquinto E; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Turin, Italy.
Pozzi C; Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Pisa FD; Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Dello Iacono L; Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Landi G; Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Tagliazucchi L; Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.
Mangani S; Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Spyrakis F; Department of Drug Science and Technology, University of Turin, Via Giuria 9, 10125 Turin, Italy.
Costi MP; Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy.