Anti-diabetic activity of a sulfated galactoarabinan with unique structural characteristics from Cladophora oligoclada (Chlorophyta).

He, Meijia; Hao, Jiejie; Feng, Changning; Yang, Yajing; Shao, Zhuling; Wang, Lei; Mao, Wenjun

He, Meijia; Hao, Jiejie; Feng, Changning; Yang, Yajing; Shao, Zhuling; Wang, Lei; Mao, Wenjun.

Afiliação

He M; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Hao J; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. Electronic address: 2009haojie@ouc.edu.cn.
Feng C; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Yang Y; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Shao Z; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Wang L; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Mao W; Key Laboratory of Marine Drugs of Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China. Electronic address: w

Carbohydr Polym ; 278: 118933, 2022 Feb 15.

Article em En | MEDLINE | ID: mdl-34973751

Assuntos

Clorófitas/química; Galactanos/farmacologia; Hipoglicemiantes/farmacologia; Polipeptídeo Amiloide das Ilhotas Pancreáticas/antagonistas & inibidores; Sulfatos/farmacologia; Animais; Células Cultivadas; Galactanos/química; Galactanos/isolamento & purificação; Hipoglicemiantes/química; Hipoglicemiantes/isolamento & purificação; Polipeptídeo Amiloide das Ilhotas Pancreáticas/metabolismo; Camundongos; Estresse Oxidativo/efeitos dos fármacos; Agregados Proteicos/efeitos dos fármacos; Espécies Reativas de Oxigênio/metabolismo; Sulfatos/química; Sulfatos/isolamento & purificação

Palavras-chave

1,1,1,3,3,3-Hexafluoro-2-propanol (PubChem CID: 13529); 2',7'-Dichlorofluorescin diacetate (PubChem CID: 77718); 3'-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (PubChem CID: 22288011); Acetic acid (PubChem CID: 176); Adenosine triphosphate (PubChem CID:5957); Anti-diabetic activity; Cladophora oligoclada; Ethanol (PubChem CID: 702); Hexamethylene diamine (PubChem CID: 16402); Structural characterization; Sulfated polysaccharide; Thioflavine T (PubChem CID: 16953); Uranyl acetate (PubChem CID: 10915); hIAPP; l-Arabinose (PubChem CID: 439195)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfatos / Clorófitas / Polipeptídeo Amiloide das Ilhotas Pancreáticas / Galactanos / Hipoglicemiantes Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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