Silver-catalyzed monofluoroalkylation of heteroarenes with α-fluorocarboxylic acids: an insight into the solvent effect.
Chem Commun (Camb)
; 58(8): 1147-1150, 2022 Jan 25.
Article
em En
| MEDLINE
| ID: mdl-34981099
ABSTRACT
A mild and efficient method for direct C-H monofluoroalkylation of heteroarenes with easily accessible and inexpensive α-fluorocarboxylic acids has been developed. This silver-catalyzed reaction affords mono- and bis-monofluoroalkylated heteroarenes in good yields under mild conditions, and the solvent effect on the monofluoroalkylation reaction is discussed in detail.
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MEDLINE
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En
Ano de publicação:
2022
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Article