Nivolumab-induced liver injury with a steroid-refractory increase in biliary enzymes, in a patient with malignant mesothelioma: An autopsy case report.
Clin Case Rep
; 9(12): e05174, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34987810
ABSTRACT
This is the first autopsy report of hepatotoxicity from nivolumab immunotherapy for malignant mesothelioma. The increase in levels of biliary enzymes and randomly distributed endothelial damage were steroid-refractory, but second-line option was abandoned because of cachexia. Further discussions are needed regarding the customized management of immune-related toxicities.
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MEDLINE
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En
Ano de publicação:
2021
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Article