Clinical impact of a deep learning system for automated detection of missed pulmonary nodules on routine body computed tomography including the chest region.
Eur Radiol
; 32(5): 2891-2900, 2022 May.
Article
em En
| MEDLINE
| ID: mdl-34999920
ABSTRACT
OBJECTIVES:
To evaluate the clinical impact of a deep learning system (DLS) for automated detection of pulmonary nodules on computed tomography (CT) images as a second reader.METHODS:
This single-centre retrospective study screened 21,150 consecutive body CT studies from September 2018 to February 2019. Pulmonary nodules detected by the DLS on axial CT images but not mentioned in initial radiology reports were flagged. Flagged images were scored by four board-certificated radiologists each with at least 5 years of experience. Nodules with scores of 2 (understandable miss) or 3 (should not be missed) were then categorised as unlikely to be clinically significant (2a or 3a) or likely to be clinically significant (2b or 3b) according to the 2017 Fleischner guidelines for pulmonary nodules. The miss rate was defined as the total number of studies receiving scores of 2 or 3 divided by total screened studies.RESULTS:
Among 172 nodules flagged by the DLS, 60 (35%) missed nodules were confirmed by the radiologists. The nodules were further categorised as 2a, 2b, 3a, and 3b in 24, 14, 10, and 12 studies, respectively, with an overall positive predictive value of 35%. Missed pulmonary nodules were identified in 0.3% of all CT images, and one-third of these lesions were considered clinically significant.CONCLUSIONS:
Use of DLS-assisted automated detection as a second reader can identify missed pulmonary nodules, some of which may be clinically significant. CLINICAL RELEVANCE/APPLICATION Use of DLS to help radiologists detect pulmonary lesions may improve patient care. KEY POINTS ⢠DLS-assisted automated detection as a second reader is feasible in a large consecutive cohort. ⢠Performance of combined radiologists and DLS was better than DLS or radiologists alone. ⢠Pulmonary nodules were missed more frequently in abdomino-pelvis CT than the thoracic CT.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Nódulo Pulmonar Solitário
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Nódulos Pulmonares Múltiplos
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Aprendizado Profundo
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Neoplasias Pulmonares
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article