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Modeling tumor plasticity in organoid models of human cancer.
Christin, John R; Shen, Michael M.
Afiliação
  • Christin JR; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Urology, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA
  • Shen MM; Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Urology, Columbia University Irving Medical Center, New York, NY 10032, USA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA
Trends Cancer ; 8(3): 161-163, 2022 03.
Article em En | MEDLINE | ID: mdl-35000880
ABSTRACT
Due to its inherent plasticity and heterogeneity, cancer is a difficult disease to model both in vitro and in vivo. However, recent advances in organoid technology hold great promise for future research into the mechanisms underlying tumor plasticity in human cancers.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Organoides / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article