Cell Membrane-Coated Electrospun Fibers Enhance Keratinocyte Growth through Cell-Type Specific Interactions.
ACS Appl Bio Mater
; 4(5): 4079-4083, 2021 05 17.
Article
em En
| MEDLINE
| ID: mdl-35006824
ABSTRACT
Although cell membrane-coated fiber scaffolds can be useful for regenerative medicine by presenting both cell surface antigens and topographical cues, it remains unknown whether changes in cellular behavior on cell membrane-coated scaffolds are due to specific cell-cell interactions. In this work, the effects of scaffold fiber diameters and surface charges on the cell membrane coating efficiency were explored. Furthermore, fibroblast membrane-coated scaffolds improved the growth of human keratinocytes as compared to red blood cell membrane-coated and plain scaffolds. These results suggest the biofunctionality of cell membrane-coated scaffolds and the specific cell-cell interactions that are preserved to modulate cellular response.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Queratinócitos
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Membrana Celular
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Materiais Revestidos Biocompatíveis
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Engenharia Tecidual
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article