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A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS.
Katz, Jonathan S; Rothstein, Jeffrey D; Cudkowicz, Merit E; Genge, Angela; Oskarsson, Björn; Hains, Avis B; Chen, Chen; Galanter, Joshua; Burgess, Braydon L; Cho, William; Kerchner, Geoffrey A; Yeh, Felix L; Ghosh, Arundhati Sengupta; Cheeti, Sravanthi; Brooks, Logan; Honigberg, Lee; Couch, Jessica A; Rothenberg, Michael E; Brunstein, Flavia; Sharma, Khema R; van den Berg, Leonard; Berry, James D; Glass, Jonathan D.
Afiliação
  • Katz JS; Forbes Norris MDA/ALS Research Center, California Pacific Medical Center, San Francisco, California, USA.
  • Rothstein JD; Johns Hopkins Hospital, Baltimore, Maryland, USA.
  • Cudkowicz ME; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Genge A; Montreal Neurological Institute & Hospital, Montreal, QC, Canada.
  • Oskarsson B; Mayo Clinic, Jacksonville, Florida, USA.
  • Hains AB; Genentech, Inc., South San Francisco, California, USA.
  • Chen C; Genentech, Inc., South San Francisco, California, USA.
  • Galanter J; Genentech, Inc., South San Francisco, California, USA.
  • Burgess BL; Genentech, Inc., South San Francisco, California, USA.
  • Cho W; Genentech, Inc., South San Francisco, California, USA.
  • Kerchner GA; F. Hoffmann-La Roche, Ltd., Basel, Switzerland.
  • Yeh FL; Genentech, Inc., South San Francisco, California, USA.
  • Ghosh AS; Genentech, Inc., South San Francisco, California, USA.
  • Cheeti S; Genentech, Inc., South San Francisco, California, USA.
  • Brooks L; Genentech, Inc., South San Francisco, California, USA.
  • Honigberg L; Genentech, Inc., South San Francisco, California, USA.
  • Couch JA; Genentech, Inc., South San Francisco, California, USA.
  • Rothenberg ME; Genentech, Inc., South San Francisco, California, USA.
  • Brunstein F; Genentech, Inc., South San Francisco, California, USA.
  • Sharma KR; University of Miami Hospital (CRC), Miami, Florida, USA.
  • van den Berg L; UMC Utrecht, Utrecht, The Netherlands.
  • Berry JD; Neurological Clinical Research Institute, Boston, Massachusetts, USA.
  • Glass JD; Emory University School of Medicine, Atlanta, Georgia, USA.
Ann Clin Transl Neurol ; 9(1): 50-66, 2022 01.
Article em En | MEDLINE | ID: mdl-35014217
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Neurofilamentos / MAP Quinase Quinase Quinases / Inibidores de Proteínas Quinases / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Neurofilamentos / MAP Quinase Quinase Quinases / Inibidores de Proteínas Quinases / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article