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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans.
Nicoli, Francesco; Cabral-Piccin, Mariela P; Papagno, Laura; Gallerani, Eleonora; Fusaro, Mathieu; Folcher, Victor; Dubois, Marion; Clave, Emmanuel; Vallet, Hélène; Frere, Justin J; Gostick, Emma; Llewellyn-Lacey, Sian; Price, David A; Toubert, Antoine; Dupré, Loïc; Boddaert, Jacques; Caputo, Antonella; Gavioli, Riccardo; Appay, Victor.
Afiliação
  • Nicoli F; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France; nclfnc1@unife.it victor.appay@inserm.fr.
  • Cabral-Piccin MP; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy.
  • Papagno L; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France.
  • Gallerani E; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France.
  • Fusaro M; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy.
  • Folcher V; Toulouse Institute for Infectious and Inflammatory Diseases, Université Toulouse III, INSERM UMR1291/CNRS UMR5051, Toulouse, France.
  • Dubois M; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France.
  • Clave E; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France.
  • Vallet H; Institut de Recherche Saint Louis, EMiLy, Université de Paris, INSERM U1160, Paris, France.
  • Frere JJ; Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Sorbonne Université, INSERM U1135, Paris, France.
  • Gostick E; Service de Gériatrie, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France.
  • Llewellyn-Lacey S; Department of Immunobiology and the Arizona Center on Aging, University of Arizona College of Medicine Tucson, Tucson, AZ.
  • Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.
  • Toubert A; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.
  • Dupré L; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, United Kingdom.
  • Boddaert J; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, United Kingdom.
  • Caputo A; Institut de Recherche Saint Louis, EMiLy, Université de Paris, INSERM U1160, Paris, France.
  • Gavioli R; Laboratoire d'Immunologie et d'Histocompatibilité, Hôpital Saint-Louis, AP-HP, Paris, France.
  • Appay V; Toulouse Institute for Infectious and Inflammatory Diseases, Université Toulouse III, INSERM UMR1291/CNRS UMR5051, Toulouse, France.
J Immunol ; 208(3): 562-570, 2022 02 01.
Article em En | MEDLINE | ID: mdl-35031578
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Linfócitos T CD8-Positivos / Metabolismo dos Lipídeos / Imunocompetência Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Linfócitos T CD8-Positivos / Metabolismo dos Lipídeos / Imunocompetência Idioma: En Ano de publicação: 2022 Tipo de documento: Article