AgNTf2-Catalyzed Regioselective C-H Alkenylation of N,N-Dialkylanilines with Ynamides.
J Org Chem
; 87(5): 2380-2392, 2022 03 04.
Article
em En
| MEDLINE
| ID: mdl-35041783
ABSTRACT
Regioselective C-H alkenylation of N,N-dialkylanilines with ynamides was developed using AgNTf2 as a catalyst. This approach represents a facile hydroarylation of ynamides, allowing for the introduction of an alkenyl group exclusively at the para position of aniline derivatives. As a result, a series of 4-alkenyl N,N-dialkylanilines were synthesized with excellent regioselectivities.
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Base de dados:
MEDLINE
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Catálise
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article