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The antigenicity of SARS-CoV-2 Delta variants aggregated 10 high-frequency mutations in RBD has not changed sufficiently to replace the current vaccine strain.
Wu, Jiajing; Nie, Jianhui; Zhang, Li; Song, Hao; An, Yimeng; Liang, Ziteng; Yang, Jing; Ding, Ruxia; Liu, Shuo; Li, Qianqian; Li, Tao; Cui, Zhimin; Zhang, Mengyi; He, Peng; Wang, Youchun; Qu, Xiaowang; Hu, Zhongyu; Wang, Qihui; Huang, Weijin.
Afiliação
  • Wu J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Nie J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Zhang L; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Song H; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 100101, Beijing, China.
  • An Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Liang Z; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Yang J; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, 100101, Beijing, China.
  • Ding R; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Liu S; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Li Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Li T; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Cui Z; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Zhang M; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • He P; Division of Hepatitis and Enteric Viral Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, 102629, Beijing, China.
  • Wang Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China.
  • Qu X; Translational Medicine Institute, First People's Hospital of Chenzhou, University of South China, Chenzhou, China.
  • Hu Z; Division of Hepatitis and Enteric Viral Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC) and Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, 102629, Beijing, China. huzhy@nifdc.org.cn.
  • Wang Q; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 100101, Beijing, China. wangqihui@im.ac.cn.
  • Huang W; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), 102629, Beijing, China. huangweijin@nifdc.org.cn.
Signal Transduct Target Ther ; 7(1): 18, 2022 01 19.
Article em En | MEDLINE | ID: mdl-35046385
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Neutralizantes / Glicoproteína da Espícula de Coronavírus / Imunogenicidade da Vacina / Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Neutralizantes / Glicoproteína da Espícula de Coronavírus / Imunogenicidade da Vacina / Vacinas contra COVID-19 / SARS-CoV-2 / COVID-19 / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article