Emerging Insights Into the Role of Epigenetics and Gut Microbiome in the Pathogenesis of Graves' Ophthalmopathy.

Wang, Yan; Ma, Xiao-Min; Wang, Xin; Sun, Xin; Wang, Ling-Jun; Li, Xin-Qi; Liu, Xiao-Yan; Yu, Hong-Song

Wang, Yan; Ma, Xiao-Min; Wang, Xin; Sun, Xin; Wang, Ling-Jun; Li, Xin-Qi; Liu, Xiao-Yan; Yu, Hong-Song.

Afiliação

Wang Y; Department of Immunology, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, China.
Ma XM; Department of Immunology, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, China.
Wang X; School of Basic Medical Sciences, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Sun X; School of Basic Medical Sciences, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Wang LJ; School of Basic Medical Sciences, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Li XQ; School of Basic Medical Sciences, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Liu XY; School of Basic Medical Sciences, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Yu HS; Department of Immunology, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, China.

Front Endocrinol (Lausanne) ; 12: 788535, 2021.

Article em En | MEDLINE | ID: mdl-35069441

Assuntos

Epigênese Genética; Fibroblastos/metabolismo; Microbioma Gastrointestinal; Oftalmopatia de Graves/genética; Inflamação/genética; Adipogenia; Metilação de DNA/genética; Fibroblastos/imunologia; Fibrose; Oftalmopatia de Graves/imunologia; Oftalmopatia de Graves/microbiologia; Código das Histonas/genética; Humanos; Imunoglobulinas Estimuladoras da Glândula Tireoide/imunologia; Inflamação/imunologia; Inflamação/metabolismo; Inflamação/microbiologia; Linfócitos T Reguladores/imunologia; Células Th17/imunologia

Palavras-chave

DNA methylation; Graves' ophthalmopathy; epigenetics; gut microbiome; histone modification; noncoding RNAs

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epigênese Genética / Oftalmopatia de Graves / Fibroblastos / Microbioma Gastrointestinal / Inflamação Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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