Your browser doesn't support javascript.
loading
Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening.
Hunter, Zoe L; Leeson, Hannah C; Shaker, Mohammed R; Wolvetang, Ernst J; Vadlamudi, Lata.
Afiliação
  • Hunter ZL; The University of Queensland, Australian Institute for Bioengineering & Nanotechnology (AIBN), St. Lucia, Brisbane, QLD 4072, Australia.
  • Leeson HC; The University of Queensland, Australian Institute for Bioengineering & Nanotechnology (AIBN), St. Lucia, Brisbane, QLD 4072, Australia.
  • Shaker MR; The University of Queensland, Australian Institute for Bioengineering & Nanotechnology (AIBN), St. Lucia, Brisbane, QLD 4072, Australia.
  • Wolvetang EJ; The University of Queensland, Australian Institute for Bioengineering & Nanotechnology (AIBN), St. Lucia, Brisbane, QLD 4072, Australia. Electronic address: e.wolvetang@uq.edu.au.
  • Vadlamudi L; The University of Queensland, UQ Centre for Clinical Research, Herston Brisbane, QLD 4029, Australia; Department of Neurology, Royal Brisbane and Women's Hospital, Herston Brisbane, QLD 4029, Australia.
Stem Cell Res ; 60: 102673, 2022 04.
Article em En | MEDLINE | ID: mdl-35074713
ABSTRACT
In this paper, we describe the generation and validation of human induced pluripotent stem cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs) from 6 epilepsy patients using a non-integrative Sendai virus vector. These human cellular models will enable patient-specific drug screening to improve outcomes for individuals with this disorder.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epilepsia / Células-Tronco Pluripotentes Induzidas Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epilepsia / Células-Tronco Pluripotentes Induzidas Idioma: En Ano de publicação: 2022 Tipo de documento: Article