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Evolution of FMT - From early clinical to standardized treatments.
Servetas, Stephanie L; Daschner, Phillip J; Guyard, Cyril; Thomas, Vincent; Affagard, Herve; Sergaki, Chrysi; Sokol, Harry; Wargo, Jennifer A; Wu, Gary D; Sabot, Philippe.
Afiliação
  • Servetas SL; Complex Microbial Systems Group, Biosystems and Biomaterials Divison, National Institute of Standards and Technology, Gaithersburg, MD, USA. Electronic address: stephanie.servetas@nist.gov.
  • Daschner PJ; Division of Cancer Biology, National Cancer Institute, Bethesda, MD, USA. Electronic address: daschnep@mail.nih.gov.
  • Guyard C; BIOASTER Technological Research Institute, Lyon, France. Electronic address: Cyril.GUYARD@bioaster.org.
  • Thomas V; BIOASTER Technological Research Institute, Lyon, France. Electronic address: Vincent.THOMAS@bioaster.org.
  • Affagard H; MaaT Pharma, 70 Avenue Tony Garnier, 69007, Lyon, France. Electronic address: haffagard@maat-pharma.com.
  • Sergaki C; Microbiome Section, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, EN6 3QG, United Kingdom. Electronic address: Chrysi.Sergaki@nibsc.org.
  • Sokol H; Assistance Publique des Hôpitaux de Paris, Saint-Antoine Hospital, Gastroenterology Department, 184 rue du faubourg Saint-Antoine 75571 Paris cedex 12, France. Electronic address: harry.sokol@aphp.fr.
  • Wargo JA; Departments of Surgical Oncology and Genomic Medicine, the University of Texas, MD Anderson Cancer Center, Houston, TX, USA. Electronic address: JWargo@mdanderson.org.
  • Wu GD; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: gdwu@pennmedicine.upenn.edu.
  • Sabot P; International Alliance for Biological Standardization, IABS, Geneva, Switzerland. Electronic address: philippe.sabot@iabs.org.
Biologicals ; 76: 31-35, 2022 Apr.
Article em En | MEDLINE | ID: mdl-35086768
Faecal microbiota transplantation (FMT) is widely reported to be an effective treatment against recurrent Clostridioides difficile infections. Recent clinical studies support the therapeutic use of FMT for several other pathologies including inflammatory bowel disease, several types of cancer, and other functional or metabolic disorders. Initial guidelines are now available to overcome some of the technical and logistical issues for establishing a non-standardized treatment into clinical practice with proper safety and governance. To aid the improvement of guidance and standardization requirements for FMT, the International Alliance for Biological Standardization (IABS) and the BIOASTER Microbiology Technology Institute hosted a joint online workshop in May of 2021. The goal of the webinar was to provide a multi-disciplinary perspective of the ongoing efforts to develop FMT guidelines including technical, regulatory, and standardization requirements. Recognized experts gave insights into state-of-the art approaches and standards developed by international organizations and institutions.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Clostridioides difficile / Infecções por Clostridium Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Inflamatórias Intestinais / Clostridioides difficile / Infecções por Clostridium Idioma: En Ano de publicação: 2022 Tipo de documento: Article