MiR-195 promotes pancreatic ß-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.

Xu, Yuhua; Tang, Zixuan; Dai, Hui; Hou, Jue; Li, Fangqin; Tang, Zhuqi; Zhang, Dongmei

Xu, Yuhua; Tang, Zixuan; Dai, Hui; Hou, Jue; Li, Fangqin; Tang, Zhuqi; Zhang, Dongmei.

Afiliação

Xu Y; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Tang Z; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Dai H; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Hou J; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Li F; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Tang Z; Department of Endocrinology, Affiliated Hospital of Nantong University, Jiangsu, China.
Zhang D; Medical Research Center, Affiliated Hospital 2 of Nantong University, Jiangsu, China.

Obesity (Silver Spring) ; 30(2): 447-459, 2022 02.

Article em En | MEDLINE | ID: mdl-35088561

Assuntos

Diabetes Mellitus Tipo 2; MicroRNAs; Animais; Desdiferenciação Celular; Diabetes Mellitus Tipo 2/genética; GTP Fosfo-Hidrolases/genética; GTP Fosfo-Hidrolases/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; MicroRNAs/genética; MicroRNAs/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus Tipo 2 Idioma: En Ano de publicação: 2022 Tipo de documento: Article