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Synthesis and Characterization of 5-(2-Fluoro-4-[11C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2.
Yuan, Gengyang; Dhaynaut, Maeva; Lan, Yu; Guehl, Nicolas J; Huynh, Dalena; Iyengar, Suhasini M; Afshar, Sepideh; Jain, Manish Kumar; Pickett, Julie E; Kang, Hye Jin; Wang, Hao; Moon, Sung-Hyun; Ondrechen, Mary Jo; Wang, Changning; Shoup, Timothy M; El Fakhri, Georges; Normandin, Marc D; Brownell, Anna-Liisa.
Afiliação
  • Yuan G; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Dhaynaut M; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Lan Y; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, United States.
  • Guehl NJ; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Huynh D; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Iyengar SM; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Afshar S; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Jain MK; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
  • Pickett JE; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
  • Kang HJ; Department of Pharmacology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
  • Wang H; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, United States.
  • Moon SH; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Ondrechen MJ; Department of Chemistry and Chemical Biology, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.
  • Wang C; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, United States.
  • Shoup TM; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • El Fakhri G; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Normandin MD; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
  • Brownell AL; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 3rd Avenue, Charlestown, Massachusetts 02129, United States.
J Med Chem ; 65(3): 2593-2609, 2022 02 10.
Article em En | MEDLINE | ID: mdl-35089713
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Picolínicos / Piranos / Receptores de Glutamato Metabotrópico / Meios de Contraste / Compostos Radiofarmacêuticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Picolínicos / Piranos / Receptores de Glutamato Metabotrópico / Meios de Contraste / Compostos Radiofarmacêuticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article