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Nematicidal activity of naphthalimide-boron cluster conjugates.
Bogucka-Kocka, Anna; Kolodziej, Przemyslaw; Makuch-Kocka, Anna; Rózycka, Daria; Rykowski, Sebastian; Nekvinda, Jan; Grüner, Bohumír; Olejniczak, Agnieszka B.
Afiliação
  • Bogucka-Kocka A; Chair and Department of Biology and Genetics, Medical University of Lublin, 4a Chodzki St., Lublin 20-093, Poland.
  • Kolodziej P; Chair and Department of Biology and Genetics, Medical University of Lublin, 4a Chodzki St., Lublin 20-093, Poland.
  • Makuch-Kocka A; Chair of Pharmacology and Biology, Department of Pharmacology, Medical University of Lublin, 4a Chodzki St., Lublin 20-093, Poland.
  • Rózycka D; Institute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., Lodz 93-232, Poland. aolejniczak@cbm.pan.pl.
  • Rykowski S; Institute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., Lodz 93-232, Poland. aolejniczak@cbm.pan.pl.
  • Nekvinda J; Institute of Inorganic Chemistry, Czech Academy of Sciences, Hlavní 1001, CZ-250 68 Rez, Czech Republic.
  • Grüner B; Institute of Inorganic Chemistry, Czech Academy of Sciences, Hlavní 1001, CZ-250 68 Rez, Czech Republic.
  • Olejniczak AB; Institute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., Lodz 93-232, Poland. aolejniczak@cbm.pan.pl.
Chem Commun (Camb) ; 58(15): 2528-2531, 2022 Feb 17.
Article em En | MEDLINE | ID: mdl-35098961
ABSTRACT
This study presents the activity of a series of 1,8-naphthalimide-carborane/metallacarborane conjugates against Rhabditis sp. The carborane conjugates were the least active. Selected conjugates with cobaltacarborane (5 and 6) showed high activity. Their lethal concentration (LC50) values are substantially lower than that of the drug mebendazole.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article