Should a prescription database be used to search uncontrolled severe asthmatics?
Adv Respir Med
; 2022 Jan 31.
Article
em En
| MEDLINE
| ID: mdl-35099058
ABSTRACT
INTRODUCTION:
Many uncontrolled severe asthmatics are not on biologic therapy. We hypothesized that using a prescription database could help us identify them. MATERIAL ANDMETHODS:
3,309 patients who received at least one Montelukast prescription in 2019 were extracted from our prescription database. Number of packages/year, types and dosages of ICS, LABA, ICS/LABA, LAMA and monoclonal antibodies were considered for each patient. In our analysis, for subjects that took > 7 packages of ICS/LABA + LTRA +/- LAMA (high adherent) the number of oral corticosteroids (OC) packets prescribed for each of them was also looked upon.RESULTS:
Patients that took ICS/LABA or ICS/LABA + LAMA continuously with high ICS doses were 188 (25.6%) and 117 (39.3%) respectively (total 305 - 29.5%). Among them, 58 (30.9%) and 53 (45.3%) (total 111 - 36.4%) were prescribed more than 2 OC packages. Whereas, 21 (11.2%) and 24 (20.5%) patients (total 45 - 14.75%) received at least 4 OC package prescriptions.CONCLUSION:
Approximately 36% of patients in continuous step-4/5 of GINA guidelines treatment may have severe uncontrolled asthma (overusing OC) which needed biologic treatment. In our opinion, a prescription archiving database may be a tool that can help us identify such uncontrolled asthma patients.
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MEDLINE
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Ano de publicação:
2022
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Article