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Distribution of Aspergillus Species and Prevalence of Azole Resistance in Respiratory Samples From Swiss Tertiary Care Hospitals.
Ragozzino, Silvio; Goldenberger, Daniel; Wright, Patrick R; Zimmerli, Stefan; Mühlethaler, Konrad; Neofytos, Dionysios; Riat, Arnaud; Boggian, Katia; Nolte, Oliver; Conen, Anna; Fankhauser, Hans; Schreiber, Peter W; Zbinden, Reinhard; Lamoth, Frederic; Khanna, Nina.
Afiliação
  • Ragozzino S; Division of Infectious Diseases and Hospital Epidemiology, University of Basel and University Hospital Basel, Basel, Switzerland.
  • Goldenberger D; Clinical Bacteriology and Mycology, University of Basel and University Hospital Basel, Basel, Switzerland.
  • Wright PR; Clinical Trial Unit, University Hospital Basel, Basel, Switzerland.
  • Zimmerli S; Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland.
  • Mühlethaler K; Clinical Microbiology, Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
  • Neofytos D; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Geneva, Geneva, Switzerland.
  • Riat A; Division of Laboratory Medicine, Laboratory of Bacteriology, University Hospital Geneva and University of Geneva, Geneva, Switzerland.
  • Boggian K; Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, St Gallen, Switzerland.
  • Nolte O; Center for Laboratory Medicine, St Gallen, Switzerland.
  • Conen A; Clinic of Infectious Diseases and Hospital Hygiene, Cantonal Hospital Aarau, Aarau, Switzerland.
  • Fankhauser H; Clinical Microbiology, Cantonal Hospital Aarau, Aarau, Switzerland.
  • Schreiber PW; Division of Infectious Diseases and Hospital Epidemiology, University of Zurich and University Hospital Zurich, Zurich, Switzerland.
  • Zbinden R; Clinical Microbiology, University Hospital Zurich, Zurich, Switzerland.
  • Lamoth F; Infectious Diseases Service and Institute of Microbiology, Lausanne University Hospital, Lausanne, Switzerland.
  • Khanna N; Division of Infectious Diseases and Hospital Epidemiology, University of Basel and University Hospital Basel, Basel, Switzerland.
Open Forum Infect Dis ; 9(2): ofab638, 2022 Feb.
Article em En | MEDLINE | ID: mdl-35111868
ABSTRACT
Among 400 Aspergillus species from respiratory samples in Switzerland, Aspergillus fumigatus was the most frequent species. Non-fumigatus Aspergillus spp were more prevalent among solid organ transplant recipients and after azole exposure. Azole resistance was detected in 4 A fumigatus isolates, 3 of them with the "environmental" mutation TR34/L98H in the cyp51A gene.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article