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Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer.
Nicolas, Adele M; Pesic, Marina; Engel, Esther; Ziegler, Paul K; Diefenhardt, Markus; Kennel, Kilian B; Buettner, Florian; Conche, Claire; Petrocelli, Valentina; Elwakeel, Eiman; Weigert, Andreas; Zinoveva, Anna; Fleischmann, Maximilian; Häupl, Björn; Karakütük, Cem; Bohnenberger, Hanibal; Mosa, Mohammed H; Kaderali, Lars; Gaedcke, Jochen; Ghadimi, Michael; Rödel, Franz; Arkan, Melek C; Oellerich, Thomas; Rödel, Claus; Fokas, Emmanouil; Greten, Florian R.
Afiliação
  • Nicolas AM; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Pesic M; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Engel E; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Ziegler PK; Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt/Main, Germany.
  • Diefenhardt M; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany; University Cancer Center Frankfurt Marburg (UCT), University Hospital Frankfurt, Frankfurt/Main, Germany.
  • Kennel KB; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Buettner F; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Medicine, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Conche C; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Petrocelli V; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Elwakeel E; Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Weigert A; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Zinoveva A; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Fleischmann M; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany; University Cancer Center Frankfurt Marburg (UCT), University Hospital Frankfurt, Frankfurt/Main, Germany.
  • Häupl B; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Medicine, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Karakütük C; Institute of Pathology, University Medical Center, Göttingen, Germany.
  • Bohnenberger H; Institute of Pathology, University Medical Center, Göttingen, Germany.
  • Mosa MH; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Kaderali L; Institute of Bioinformatics, University Medicine Greifswald, Greifswald, Germany.
  • Gaedcke J; Department of Surgery, University Medical Center, Göttingen, Germany.
  • Ghadimi M; Department of Surgery, University Medical Center, Göttingen, Germany.
  • Rödel F; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany; University Cancer Center Frankfurt Marburg (UCT), University Hospital Frankfurt, Frankfurt/Main, Germany.
  • Arkan MC; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Oellerich T; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Medicine, Goethe University Frankfurt, Frankfurt/Main, Germany.
  • Rödel C; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany; University Cancer Center Frankfurt Marburg (UCT), University Hospital Frankfurt, Frankfurt/Main, Germany; German Cancer Con
  • Fokas E; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; Department of Radiotherapy and Oncology, Goethe University Frankfurt, Frankfurt/Main, Germany; University Cancer Center Frankfurt Marburg (UCT), University Hospital Frankfurt, Frankfurt/Main, Germany; German Cancer Con
  • Greten FR; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt/Main, Germany; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt/Main, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic ad
Cancer Cell ; 40(2): 168-184.e13, 2022 02 14.
Article em En | MEDLINE | ID: mdl-35120600
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Resistencia a Medicamentos Antineoplásicos / Microambiente Tumoral / Fibroblastos Associados a Câncer Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Resistencia a Medicamentos Antineoplásicos / Microambiente Tumoral / Fibroblastos Associados a Câncer Idioma: En Ano de publicação: 2022 Tipo de documento: Article