Ionic mitigation of CD4<sup>+</sup> T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.

Krone, Anna; Fu, Yan; Schreiber, Simon; Kotrba, Johanna; Borde, Loisa; Nötzold, Aileen; Thurm, Christoph; Negele, Jonas; Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Garbers, Christoph; Shukla, Aniruddh; Geffers, Robert; Schraven, Burkhart; Reinhold, Dirk; Dudeck, Anne; Reinhold, Annegret; Müller, Andreas J; Kahlfuss, Sascha

Ionic mitigation of CD4⁺ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc.

Krone, Anna; Fu, Yan; Schreiber, Simon; Kotrba, Johanna; Borde, Loisa; Nötzold, Aileen; Thurm, Christoph; Negele, Jonas; Franz, Tobias; Stegemann-Koniszewski, Sabine; Schreiber, Jens; Garbers, Christoph; Shukla, Aniruddh; Geffers, Robert; Schraven, Burkhart; Reinhold, Dirk; Dudeck, Anne; Reinhold, Annegret; Müller, Andreas J; Kahlfuss, Sascha.

Afiliação

Krone A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Fu Y; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Schreiber S; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Kotrba J; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Borde L; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Nötzold A; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Thurm C; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Negele J; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Franz T; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Stegemann-Koniszewski S; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Schreiber J; Experimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.
Garbers C; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.
Shukla A; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Geffers R; Experimental Pneumology, Department of Pneumology, University Hospital Magdeburg/Medical Faculty, Otto-von-Guericke-University, Magdeburg, Germany.
Schraven B; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.
Reinhold D; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Dudeck A; Institute of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Reinhold A; Health Campus Immunology, Infectiology and Inflammation (GCI3), Medical Faculty, Otto-Von-Guericke University Magdeburg, Magdeburg, Germany.
Müller AJ; Center for Health and Medical Prevention (CHaMP), Otto-von-Guericke-University, Magdeburg, Germany.
Kahlfuss S; Institute of Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

Sci Rep ; 12(1): 1943, 2022 02 04.

Article em En | MEDLINE | ID: mdl-35121767

Assuntos

Ácido Aspártico/análogos & derivados; Asma/tratamento farmacológico; Sistema Nervoso Central/efeitos dos fármacos; Encefalomielite Autoimune Experimental/tratamento farmacológico; Metabolismo Energético/efeitos dos fármacos; Agentes de Imunomodulação/farmacologia; Pulmão/efeitos dos fármacos; Ativação Linfocitária/efeitos dos fármacos; Pneumonia/tratamento farmacológico; Células Th1/efeitos dos fármacos; Células Th2/efeitos dos fármacos; Compostos de Zinco/farmacologia; Animais; Ácido Aspártico/farmacologia; Asma/genética; Asma/imunologia; Asma/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Sistema Nervoso Central/imunologia; Sistema Nervoso Central/metabolismo; Encefalomielite Autoimune Experimental/genética; Encefalomielite Autoimune Experimental/imunologia; Encefalomielite Autoimune Experimental/metabolismo; Metabolismo Energético/genética; Regulação da Expressão Gênica; Pulmão/imunologia; Pulmão/metabolismo; Ativação Linfocitária/genética; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Pneumonia/genética; Pneumonia/imunologia; Pneumonia/metabolismo; Pyroglyphidae/imunologia; Transdução de Sinais; Células Th1/imunologia; Células Th1/metabolismo; Células Th2/imunologia; Células Th2/metabolismo; Transcrição Gênica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / Asma / Ativação Linfocitária / Sistema Nervoso Central / Ácido Aspártico / Compostos de Zinco / Células Th2 / Células Th1 / Encefalomielite Autoimune Experimental / Metabolismo Energético Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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