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Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors.
Xi, Meiyang; Feng, Chengjie; Du, Kui; Lv, Weiping; Du, Chenxi; Shen, Runpu; Sun, Haopeng.
Afiliação
  • Xi M; College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000, China.
  • Feng C; College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000, China; Zhejiang Engineering Research Center of Fat-soluble Vitamin, Shaoxing University, Shaoxing 312000, China.
  • Du K; College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000, China.
  • Lv W; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
  • Du C; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
  • Shen R; College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000, China; Zhejiang Engineering Research Center of Fat-soluble Vitamin, Shaoxing University, Shaoxing 312000, China. Electronic address: srunpu@usx.edu.cn.
  • Sun H; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. Electronic address: sunhaopeng@163.com.
Bioorg Med Chem Lett ; 61: 128602, 2022 04 01.
Article em En | MEDLINE | ID: mdl-35124202
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Butirilcolinesterase / Desenho de Fármacos / Inibidores da Colinesterase / Doença de Alzheimer Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Butirilcolinesterase / Desenho de Fármacos / Inibidores da Colinesterase / Doença de Alzheimer Idioma: En Ano de publicação: 2022 Tipo de documento: Article