Adipose invariant NKT cells interact with CD1d-expressing macrophages to regulate obesity-related inflammation.

Satoh, Masashi; Iizuka, Misao; Majima, Masataka; Ohwa, Chizuru; Hattori, Akito; Van Kaer, Luc; Iwabuchi, Kazuya

Satoh, Masashi; Iizuka, Misao; Majima, Masataka; Ohwa, Chizuru; Hattori, Akito; Van Kaer, Luc; Iwabuchi, Kazuya.

Afiliação

Satoh M; Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan.
Iizuka M; Program in Cellular Immunology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Majima M; Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan.
Ohwa C; Department of Pharmacology, Kitasato University School of Medicine, Sagamihara, Japan.
Hattori A; Program in Molecular Pharmacology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Van Kaer L; Program in Cellular Immunology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.
Iwabuchi K; Program in Cellular Immunology, Graduate School of Medical Sciences, Kitasato University, Sagamihara, Japan.

Immunology ; 165(4): 414-427, 2022 04.

Article em En | MEDLINE | ID: mdl-35137411

Assuntos

Diabetes Mellitus Tipo 2; Resistência à Insulina; Células T Matadoras Naturais; Tecido Adiposo/metabolismo; Animais; Antígenos CD1d; Inflamação/metabolismo; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Obesidade/metabolismo

Palavras-chave

NKT cell; Th1; diabetes; inflammation; macrophage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Células T Matadoras Naturais Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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