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Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale.
Ahmad, Imad A Haidar; Losacco, Gioacchino Luca; Shchurik, Vladimir; Wang, Xiao; Cohen, Ryan D; Herron, Alastair N; Aiken, Sheenagh; Fiorito, Daniele; Wang, Heather; Reibarkh, Mikhail; Nowak, Timothy; Makarov, Alexey A; Stoll, Dwight R; Guillarme, Davy; Mangion, Ian; Aggarwal, Varinder K; Yu, Jin-Quan; Regalado, Erik L.
Afiliação
  • Ahmad IAH; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Losacco GL; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Shchurik V; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Wang X; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Cohen RD; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Herron AN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Aiken S; School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
  • Fiorito D; School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
  • Wang H; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Reibarkh M; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Nowak T; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Makarov AA; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Stoll DR; Department of Chemistry, Gustavus Adolphus College, Saint Peter, MN 56082, USA.
  • Guillarme D; School of Pharmaceutical Sciences, University of Geneva, CMU, Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
  • Mangion I; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU, Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
  • Aggarwal VK; Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ 07065, USA.
  • Yu JQ; School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK.
  • Regalado EL; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
Angew Chem Int Ed Engl ; 61(21): e202117655, 2022 05 16.
Article em En | MEDLINE | ID: mdl-35139257
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article