A Series of BRAF- and NRAS-Driven Murine Melanoma Cell Lines with Inducible Gene Modulation Capabilities.

Bok, Ilah; Angarita, Ariana; Douglass, Stephen M; Weeraratna, Ashani T; Karreth, Florian A.

Afiliação

Bok I; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Angarita A; Cancer Biology PhD program, Department of Cell Biology, Microbiology and Molecular Biology, College of Arts and Sciences, University of South Florida, Tampa, Florida, USA.
Douglass SM; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Weeraratna AT; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Karreth FA; Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

JID Innov ; 2(2): 100076, 2022 Mar.

Article em En | MEDLINE | ID: mdl-35146482

Palavras-chave

BCC, BrafV600E Cdkn2aΔ/Δ; BPP, BrafV600E PtenΔ/Δ; CHC, collagen homing cassette; Dox, doxycycline; ESC, embryonic stem cell; FBS, fetal bovine serum; GEMM, genetically engineered mouse model; NCC, NrasQ61R Cdkn2aΔ/Δ; NPP, NrasQ61R PtenΔ/Δ; RMCE, recombination-mediated cassette exchange; sgRNA, single-guide RNA

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article