Exploration of potential inhibitors for autophagy-related protein 8 as antileishmanial agents.

Rahman, Fazlur; Ali, Rahat; Tabrez, Shams; Mobeen, Ahmed; Akand, Sajjadul Kadir; Arish, Mohd; AlAsmari, Abdullah F; Ali, Nemat; Rub, Abdur

Rahman, Fazlur; Ali, Rahat; Tabrez, Shams; Mobeen, Ahmed; Akand, Sajjadul Kadir; Arish, Mohd; AlAsmari, Abdullah F; Ali, Nemat; Rub, Abdur.

Afiliação

Rahman F; Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi, India.
Ali R; Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi, India.
Tabrez S; Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi, India.
Mobeen A; Institute of Genomics and Integrative Biology, New Delhi, India.
Akand SK; Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi, India.
Arish M; Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
AlAsmari AF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Ali N; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Rub A; Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi, India.

Chem Biol Drug Des ; 99(6): 816-827, 2022 06.

Article em En | MEDLINE | ID: mdl-35147279

Assuntos

Antiprotozoários; Família da Proteína 8 Relacionada à Autofagia; Leishmania donovani; Antiprotozoários/química; Antiprotozoários/farmacologia; Família da Proteína 8 Relacionada à Autofagia/antagonistas & inibidores; Família da Proteína 8 Relacionada à Autofagia/química; Família da Proteína 8 Relacionada à Autofagia/metabolismo; Cumarínicos/química; Cumarínicos/farmacologia; Humanos; Leishmania donovani/efeitos dos fármacos; Leishmaniose Visceral/tratamento farmacológico; Leishmaniose Visceral/metabolismo; Simulação de Acoplamento Molecular; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Leishmania donovani; Apoptosis; atg8; urolithin A

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leishmania donovani / Família da Proteína 8 Relacionada à Autofagia / Antiprotozoários Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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