Enhanced Immunomodulatory Effect of Intravenous Immunoglobulin by Fc Galactosylation and Nonfucosylation.

Mimura, Yusuke; Mimura-Kimura, Yuka; Saldova, Radka; Rudd, Pauline M; Jefferis, Roy

Mimura, Yusuke; Mimura-Kimura, Yuka; Saldova, Radka; Rudd, Pauline M; Jefferis, Roy.

Afiliação

Mimura Y; Department of Clinical Research, National Hospital Organization Yamaguchi Ube Medical Center, Ube, Japan.
Mimura-Kimura Y; Department of Clinical Research, National Hospital Organization Yamaguchi Ube Medical Center, Ube, Japan.
Saldova R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Dublin, Ireland.
Rudd PM; UCD School of Medicine, College of Health and Agricultural Science, University College Dublin, Dublin, Ireland.
Jefferis R; NIBRT GlycoScience Group, National Institute for Bioprocessing Research and Training, Dublin, Ireland.

Front Immunol ; 13: 818382, 2022.

Article em En | MEDLINE | ID: mdl-35154135

Assuntos

Citotoxicidade Celular Dependente de Anticorpos/imunologia; Artrite/tratamento farmacológico; Imunoglobulinas Intravenosas/farmacologia; Receptores de IgG/imunologia; Rituximab/farmacologia; Animais; Fucose/imunologia; Glicosilação; Humanos; Camundongos; Projetos Piloto

Palavras-chave

FcÎ³ receptor; antibody-dependent cellular cytotoxicity; autoimmune disease; glycoengineering; intravenous immunoglobulin; natural killer cell; oligosaccharide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite / Imunoglobulinas Intravenosas / Receptores de IgG / Rituximab / Citotoxicidade Celular Dependente de Anticorpos Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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