Cell-Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy.
Int J Mol Sci
; 23(3)2022 Jan 20.
Article
em En
| MEDLINE
| ID: mdl-35163034
ABSTRACT
It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between gametes is a universal requirement. Thus, there should be specific properties for the adhesion proteins involved in mating. Biochemical and biophysical studies have revealed structural information about mating adhesins, as well as their specificities and affinities, leading to some ideas about these specialized adhesion proteins. Recently, single-cell force spectroscopy (SCFS) has added important findings. In SCFS, mating cells are brought into contact in an atomic force microscope (AFM), and the adhesive forces are monitored through the course of mating. The results have shown some remarkable characteristics of mating adhesins and add knowledge about the design and evolution of mating adhesins.
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Base de dados:
MEDLINE
Assunto principal:
Adesão Celular
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Comunicação Celular
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Microscopia de Força Atômica
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Análise de Célula Única
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article