Senescent chondrogenic progenitor cells derived from articular cartilage of knee osteoarthritis patients contributes to senescence-associated secretory phenotype via release of IL-6 and IL-8.

Jacob, Justin; Aggarwal, Anjali; Aggarwal, Aditya; Bhattacharyya, Shalmoli; Kumar, Vishal; Sharma, Vinit; Sahni, Daisy

Jacob, Justin; Aggarwal, Anjali; Aggarwal, Aditya; Bhattacharyya, Shalmoli; Kumar, Vishal; Sharma, Vinit; Sahni, Daisy.

Afiliação

Jacob J; Department of Anatomy, Research Block B, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: jjcruci67@gmail.com.
Aggarwal A; Department of Anatomy, Research Block B, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: anjli_doc@yahoo.com.
Aggarwal A; Department of Orthopedics, Nehru Hospital, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: adityadocpgi@gmail.com.
Bhattacharyya S; Department of Biophysics, Research Block B, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: shalmoli2007@yahoo.co.in.
Kumar V; Department of Orthopedics, Nehru Hospital, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: drkumarvishal@gmail.com.
Sharma V; Department of Anatomy, Research Block B, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: vntsharma58@gmail.com.
Sahni D; Department of Anatomy, Research Block B, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: daisy_sahni@rediffmail.com.

Acta Histochem ; 124(3): 151867, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35192993

Assuntos

Cartilagem Articular; Condrócitos; Interleucina-6; Interleucina-8; Osteoartrite do Joelho; Células-Tronco; Cartilagem Articular/metabolismo; Cartilagem Articular/patologia; Humanos; Interleucina-6/metabolismo; Interleucina-8/metabolismo; Fenótipo Secretor Associado à Senescência; Células-Tronco/metabolismo; Células-Tronco/patologia

Palavras-chave

Articular cartilage; Cellular senescence; Chondrogenic progenitor cells; Knee osteoarthritis; Senescence-associated secretory phenotype

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Cartilagem Articular / Interleucina-8 / Interleucina-6 / Condrócitos / Osteoartrite do Joelho Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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