Breakthrough Trichosporon asahii in a Patient With New Diagnosis B-ALL on Echinocandin Prophylaxis: A Case Report.
J Pediatr Hematol Oncol
; 44(2): e514-e517, 2022 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-35200226
ABSTRACT
Invasive fungal disease is a difficult to diagnose complication of therapy in patients with hematologic malignancy. Antifungal prophylaxis is recommended in high-risk populations, but its use in other populations is less clear. This brief report describes a patient with Trisomy 21 on caspofungin prophylaxis who died of disseminated Trichosporon asahii during induction therapy for new diagnosis low-risk B-cell acute lymphoblastic leukemia, accompanied by a review of similar cases in the literature. Her case highlights the utility of relatively novel diagnostic modalities and reinforces the need for caution in placing patients on antifungal prophylaxis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Basidiomycota
/
Trichosporon
/
Tricosporonose
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article