Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.

Cirinelli, Angelo; Wheelan, Justin; Grieg, Christopher; Molina, Carlos A

Cirinelli, Angelo; Wheelan, Justin; Grieg, Christopher; Molina, Carlos A.

Afiliação

Cirinelli A; Department of Biology, Montclair State University, Montclair, NJ, 07043, USA; Molecular Biology and Genetics Program, Rutgers New Jersey Medical School, Newark, NJ, 07103, USA.
Wheelan J; Department of Biology, Montclair State University, Montclair, NJ, 07043, USA; Environmental Science and Management Program, Montclair State University, Montclair, NJ, 07043, USA.
Grieg C; Department of Biology, Montclair State University, Montclair, NJ, 07043, USA; Molecular Biology and Genetics Program, Rutgers New Jersey Medical School, Newark, NJ, 07103, USA.
Molina CA; Department of Biology, Montclair State University, Montclair, NJ, 07043, USA; Environmental Science and Management Program, Montclair State University, Montclair, NJ, 07043, USA. Electronic address: molinac@montclair.edu.

Exp Cell Res ; 414(1): 113083, 2022 05 01.

Article em En | MEDLINE | ID: mdl-35227662

Assuntos

Modulador de Elemento de Resposta do AMP Cíclico; Complexo de Endopeptidases do Proteassoma; Ubiquitina-Proteína Ligases; Linhagem Celular Tumoral; Modulador de Elemento de Resposta do AMP Cíclico/metabolismo; Humanos; Complexo de Endopeptidases do Proteassoma/metabolismo; Proteólise; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação

Palavras-chave

Cancer; ICER; N-End rule; NAA15; UBR4; Ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Complexo de Endopeptidases do Proteassoma / Modulador de Elemento de Resposta do AMP Cíclico Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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