Heterotopic Gastric Mucosa in Middle Esophagus Complicated with Esophageal Ulcers.
Intern Med
; 61(18): 2735-2740, 2022 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-35228416
ABSTRACT
Heterotopic gastric mucosa (HGM) of esophagus, primarily occurring in cervical esophagus, is usually asymptomatic. A healthy woman (mid-40s) with postprandial heartburn was diagnosed with middle esophageal HGM and esophageal ulcers by esophagogastroduodenoscopy. Using 8-channel pH monitoring, a sensor near the HGM area detected postprandial acid phase (pH 3-4), while areas adjacent to the proximal and distal sensors were neutral, suggesting acid secretion from the HGM. A biopsy showed fundic gland tissue expressing H+/K+-ATPase and pepsinogen-I. Oral vonoprazan improved the clinical symptoms and endoscopic findings. This is the first report using 8-channel pH monitoring to diagnose extremely rare middle esophageal HGM.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Úlcera Péptica
/
Coristoma
/
Doenças do Esôfago
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article