Protein-Induced Fluorescence Enhancement and Quenching in a Homogeneous DNA-Based Assay for Rapid Detection of Small-Molecule Drugs in Human Plasma.

Nielsen, Line D F; Hansen-Bruhn, Malthe; Nijenhuis, Minke A D; Gothelf, Kurt V

Nielsen, Line D F; Hansen-Bruhn, Malthe; Nijenhuis, Minke A D; Gothelf, Kurt V.

Afiliação

Nielsen LDF; Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
Hansen-Bruhn M; Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
Nijenhuis MAD; Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
Gothelf KV; Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.

ACS Sens ; 7(3): 856-865, 2022 03 25.

Article em En | MEDLINE | ID: mdl-35239321

Assuntos

DNA; Dabigatrana; DNA/metabolismo; Transferência Ressonante de Energia de Fluorescência/métodos; Humanos; Proteínas

Palavras-chave

DNA biosensor; PIFE; PIFQ; homogeneous assay; immunoassay; point of care; quantification; small-molecule detection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Dabigatrana Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Dabigatrana Idioma: En Ano de publicação: 2022 Tipo de documento: Article